The team

The Nano2BIO team, in October 2025

Permanent members : Céline Elie-Caille, Wilfrid Boireau, Jérome Dejeu, Benjamin Brunel, Alain Rouleau

Contractual members : Eugénie Vidal, Sylvain Midrouet, Almar Al Assaad

PhD students : Mohamed Kouryani, Doha Zorkot

Interns : Julie Camus
 


 

 

Céline Élie-Caille

Associate Professor – University of Franche-Comté

Head of the Nano2BIO team

Expertise in Atomic Force Microscopy for the qualification of multi-scale biological objects, from molecules to cells, in Micronanostructuring of substrates, in Purification and reconstitution of membrane proteins in proteoliposomes and supported lipid bilayers.

https://www.femto-st.fr/fr/personnel-femto/celineelie

https://scholar.google.fr/citations?user=UEIrR_MAAAAJ&hl=fr

https://www.linkedin.com/in/celine-elie-caille-296617109/?originalSubdomain=fr

Mail : caille@femto-st.fr
 

Tel : 0381666607

Wilfrid Boireau

Research Director - CNRS

CLIPP platform Manager

Expertise in supramolecular engineering, functional biointerfaces, biophysical characterization of molecular interactions, qualification of multi-scale biological targets (molecules, extracellular vesicles, cells) in biofluids.

https://www.femto-st.fr/fr/personnel-femto/wilfridboireau

https://scholar.google.com/citations?user=OefjStAAAAAJ&hl=en&oi=ao

https://www.linkedin.com/in/wilfrid-boireau-402102b4/

Mail : wboireau@femto-st.fr
 

Tel : 0381666607

Jérome Dejeu

Associate Professor – SUPMICROTECH ENSMM

Expertise in surface functionalization, biophysical characterization of molecular interactions (DNA, proteins, sugars, etc.): kinetics and thermodynamics.

https://www.femto-st.fr/fr/personnel-femto/jeromedejeu2

https://www.webofscience.com/wos/author/record/B-5745-2013?state=%7B%7D

https://scholar.google.fr/citations?hl=fr&user=MjY3LeIAAAAJ&view_op=list_works

https://www.linkedin.com/in/j%C3%A9r%C3%B4me-dejeu-862049171/

Mail : jerome.dejeu2@femto-st.fr
 

Tel : 0363082623

Benjamin Brunel

Associate Professor - ISIFC

Expertise in Raman spectroscopy, focusing on optical aspects (Raman microscopy, SERS) and data analysis (chemometrics, machine learning), applied to the analysis of biological samples (tissue histological sections, cells, EVs).

https://www.femto-st.fr/fr/personnel-femto/benjaminbrunel

https://scholar.google.fr/citations?user=R58AkoAAAAAJ&hl=fr

https://www.linkedin.com/in/benjamin-brunel-755699b2/

Mail : benjamin.brunel@femto-st.fr
 

Tel : 0363082476

Alain Rouleau

Engineer - University of Franche-Comté

Specialized in biology (immunology, physiology, oncology, in vitro diagnostics), works at the FEMTO-ST Institute in Besançon. He participates in projects on bio-interactions (Surface Plasmon Resonance), the development of biological sensors, and optical, biochemical, and biophysical characterization. He is also the technical manager of the CLIPP proteomics platform.
 
Mail : alain.rouleau@femto-st.fr
 
 
 
 

Eugénie Vidal

Engineer

Engineer, recruited on ENDOMITOPAH ANR project (2024-2027)
Developing a method for characterization and lysis of extracellular vesicles for subsequent proteomic analysis.
Mail : eugenie.vidal@femto-st.fr
 

Sylvain Midrouet

Research Engineer - UFC

Focusing on replicating coagulation process in microfluidic and biomimetic chips.

Recruited on EV TEST Project in order to characterize sub-populations of EVs using an immunocapture module (FEMTO-ST, Besançon) coupled with a hydrodynamic sorting module (LAAS, Toulouse).

Mail : sylvain.midrouet@femto-st.fr

https://www.linkedin.com/in/sylvain-midrouet-11aa1483/

Almar Al Assaad

Recruited as a research engineer for the I-NanoT project, her mission is the comprehensive characterization of various types of therapeutic and theranostic nanovectors. This will be achieved using her core expertise in Raman spectroscopy and data analysis, added to a range of key biophysical techniques such as SPRi, BLI, and AFM

Mohamed Kouryani

PhD student

PhD student (2nd year)
 
Development of a Biochip compatible with surface-enhanced Raman spectroscopy (SERS) and surface plasmon resonance (SPR) for the characterization of extracellular vesicles.
Mail : mohamed.kouryani@femto-st.fr
 

Doha Zorkot
 

PhD student

PhD student (2nd year)


Multiscale and dynamic analysis by multiplex nanobiochips of secretomes from macrophages and fibrogenic cells.


Mail : doha.zorkot@femto-st.fr

Julie CAMUS 

BUT Intern

Development of regenerable streptavidin biointerface on biochip